Maximum dermal use level: 0.7% to avoid phototoxicity
The International Fragrance Association (IFRA) recommends that Lime oil be limited to 0.7% (about 4 drops per ounce of any other carrier oils) for leave-on products like ointments, creams, and lotions used on skin exposed to sunlight. There is no restriction for body washes, shampoos, soaps, and other wash-off products because the oil does not remain on the skin.
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Lime is a small evergreen tree that produces a small, sour fruit very similar to Lemon. The fruits themselves are green in color with a fleshy interior. Historically, limes were used to prevent sailors from developing scurvy.
Lime is indigenous to Asia and is now cultivated in numerous countries like America, West Indies and Italy. This evergreen tree bears white flowers and glittering green fruits. India is the largest Lime oil producing country in the world and Lime was introduced into Europe initially by the Moors and was then spread slowly to America. Lime essential oil is extracted by cold press method from the peel of the fruit.
The leaves of the Lime tree were used in the prehistoric period for treating poisonous bites and swellings. Apart from its medicinal uses, Lime has been used in making pickles, sauces, desserts, jams, confections, sorbets, marmalades, beverages, squashes, perfumes, household cleaners, detergents, soaps, cosmetics and other beauty products.
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Lime essential oil has a photosensitizing effect that can cause irritation of the skin, allergic reactions, burning sensation, phytophotodermatitis, hyperpigmentation (change of skin color, visible especially in people with white skin complexion) and certain other effects. The photosensitizing effect can last up to 12 hours after application.
The primary chemical constituent responsible for the photo-carcinogenic, skin sensitizing and other topical effects of the essential oil of Lime is Limonene and certain other furanocoumarins.
A 2014 study published in the Journal of Community Hospital Internal Medicine Perspectives reveals about a skin condition called as phytophotodermatitis, induced by Lime, where a 24-year old nurse came up with red demarcated tender patches and crusted vesicles after squeezing fresh limes and going out in sun on a bright day.
Phytophotodermatitis is defined as a nonimmunologic eruption of the skin that occurs after its contact with phototoxic components in certain plant varieties and is then exposed to ultraviolet A (UVA) radiation through visible sunlight.
Few other studies also witness the effects of photosensitization of Lime and Lime-based products containing psoralens, paving the way for burns, blisters, bullae, eruption, erythematous vesicles, rashes, inflammation and hyperpigmentation. It is also been said that in certain severe cases, systemic toxicity come with the rashes, which includes nausea, vomiting and fever.
Lime oil has also been reported to promote tumors, when tested on rats where most of the papillomas were benign and few were malignant.
The safe dilution level of Lime oil is 0.7%, which is 4.2 drops per ounce of any carrier oils as per the International Fragrance Association (IFRA). This safe dilution level applies only for leave-on products like lotions and creams and is not applicable for wash-away products like soaps, shampoos and other bathing products.
Lime oil has ‘Generally Recognized As Safe (GRAS)’status by FDA (U.S. Food and Drug Administration). As per the European regulatory body, essential oils with furanocoumarins must be used in such a way that the level of bergapten should not go beyond 15ppm (parts per million) in ready to use cosmetic products after which the skin is subjected to exposure of direct sunlight and this does not apply for wash-off products. The level of bergapten should be 1 ppm in bronzing and sun protection products.
For your information, Furocoumarins are also used in healing practices on par with long-wave ultraviolet light therapy for treating vitiligo, psoriasis and mycosis fungoides.
Visit AyurvedicOils.com for more information on the traditional ayurvedic and aromatherapeutic uses of Lime Oil. Learn about the natural chemical components that give Lime Oil its fragrance and therapeutic characteristics.
Reference Links Substantiating the Possible Skin Issues of Lime Oil: